Allergic Challenge–Elicited Lipid Bodies Compartmentalize In Vivo Leukotriene C(4) Synthesis within Eosinophils

Eosinophils are an important source of leukotriene (LT)C(4), which can be synthesized within lipid bodies—cytoplasmic organelles where eicosanoid formation may take place. Allergy-driven lipid body formation and function have never been investigated. Here, we studied the in vivo induction and role o...

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Autori principali: Vieira-de-Abreu, Adriana, Assis, Edson F., Gomes, Gleice S., Castro-Faria-Neto, Hugo C., Weller, Peter F., Bandeira-Melo, Christianne, Bozza, Patrícia T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715315/
https://ncbi.nlm.nih.gov/pubmed/15947420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0145OC
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