Retinoic acid and arsenic trioxide sensitize acute promyelocytic leukemia cells to ER stress

Retinoic acid (RA) in association with chemotherapy or with arsenic trioxide (ATO) results in high cure rates of acute promyelocytic leukemia (APL). We show that RA-induced differentiation of human leukemic cell lines and primary blasts dramatically increases their sensitivity to endoplasmic reticul...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Leukemia
Hlavní autoři: Masciarelli, S, Capuano, E, Ottone, T, Divona, M, De Panfilis, S, Banella, C, Noguera, N I, Picardi, A, Fontemaggi, G, Blandino, G, Lo-Coco, F, Fazi, F
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808088/
https://ncbi.nlm.nih.gov/pubmed/28776567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.231
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky