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Retinoic acid and arsenic trioxide sensitize acute promyelocytic leukemia cells to ER stress
Retinoic acid (RA) in association with chemotherapy or with arsenic trioxide (ATO) results in high cure rates of acute promyelocytic leukemia (APL). We show that RA-induced differentiation of human leukemic cell lines and primary blasts dramatically increases their sensitivity to endoplasmic reticul...
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| Publicado no: | Leukemia |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808088/ https://ncbi.nlm.nih.gov/pubmed/28776567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.231 |
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