Tamibarotene in patients with acute promyelocytic leukaemia relapsing after treatment with all-trans retinoic acid and arsenic trioxide

Treatment of acute promyelocytic leukaemia (APL) with arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) is highly effective first-line therapy, although approximately 5–10% of patients relapse. Tamibarotene is a synthetic retinoid with activity in APL patients who relapse after chemotherapy...

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Pubblicato in:Br J Haematol
Autori principali: Sanford, David, Lo-Coco, Francesco, Sanz, Miguel A., Bona, Eros Di, Coutre, Steven, Altman, Jessica K., Wetzler, Meir, Allen, Steven L., Ravandi, Farhad, Kantarjian, Hagop, Cortes, Jorge E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770883/
https://ncbi.nlm.nih.gov/pubmed/26205361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13607
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