Clinical Application of Picodroplet Digital PCR Technology for Rapid Detection of EGFR T790M in Next-Generation Sequencing Libraries and DNA from Limited Tumor Samples

Although next-generation sequencing (NGS) is a robust technology for comprehensive assessment of EGFR-mutant lung adenocarcinomas with acquired resistance to tyrosine kinase inhibitors, it may not provide sufficiently rapid and sensitive detection of the EGFR T790M mutation, the most clinically rele...

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Bibliographic Details
Published in:J Mol Diagn
Main Authors: Borsu, Laetitia, Intrieri, Julie, Thampi, Linta, Yu, Helena, Riely, Gregory, Nafa, Khedoudja, Chandramohan, Raghu, Ladanyi, Marc, Arcila, Maria E.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807920/
https://ncbi.nlm.nih.gov/pubmed/27631691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2016.07.004
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