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Clinical Application of Picodroplet Digital PCR Technology for Rapid Detection of EGFR T790M in Next-Generation Sequencing Libraries and DNA from Limited Tumor Samples

Although next-generation sequencing (NGS) is a robust technology for comprehensive assessment of EGFR-mutant lung adenocarcinomas with acquired resistance to tyrosine kinase inhibitors, it may not provide sufficiently rapid and sensitive detection of the EGFR T790M mutation, the most clinically rele...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Mol Diagn
Κύριοι συγγραφείς: Borsu, Laetitia, Intrieri, Julie, Thampi, Linta, Yu, Helena, Riely, Gregory, Nafa, Khedoudja, Chandramohan, Raghu, Ladanyi, Marc, Arcila, Maria E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Investigative Pathology 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807920/
https://ncbi.nlm.nih.gov/pubmed/27631691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2016.07.004
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