IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene

Recently we described that endonuclease inactive DNase I translocated into the nucleus in response to increased endogenous IL-1β expression. Here, we demonstrate impact and function of translocated DNase I in tubular cells. Effect of cytokines on expression level and nuclear localisation of DNase I...

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Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Thiyagarajan, Dhivya, Pedersen, Hege L., Seredkina, Natalya, Horvei, Kjersti D., Arranz, Lorena, Sonneveld, Ramon, Nijenhuis, Tom, van der Vlag, Johan, Rekvig, Ole P.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Cell and Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807897/
https://ncbi.nlm.nih.gov/pubmed/29468159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00007
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