A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed

Recent studies have reported intrinsic metabolic reprogramming in Pkd1 knock-out cells, implicating dysregulated cellular metabolism in the pathogenesis of polycystic kidney disease. However, the exact nature of the metabolic changes and their underlying cause remains controversial. We show herein t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lin, Cheng-Chao, Kurashige, Mahiro, Liu, Yi, Terabayashi, Takeshi, Ishimoto, Yu, Wang, Tanchun, Choudhary, Vineet, Hobbs, Ryan, Liu, Li-Ka, Lee, Ping-Hsien, Outeda, Patricia, Zhou, Fang, Restifo, Nicholas P., Watnick, Terry, Kawano, Haruna, Horie, Shigeo, Prinz, William, Xu, Hong, Menezes, Luis F., Germino, Gregory G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807443/
https://ncbi.nlm.nih.gov/pubmed/29426897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20856-6
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