Effects of STING stimulation on macrophages: STING agonists polarize into “classically” or “alternatively” activated macrophages?

Stimulator of interferon genes (STING) was defined as an important molecule for promoting antitumor immunity through mediating type I interferon (IFN) production by sensing its ligands such as cyclic GMP-AMP (cGAMP). Our recent study indeed demonstrated that intratumoral injection of cGAMP showed ef...

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Bibliografski detalji
Izdano u:Hum Vaccin Immunother
Glavni autori: Ohkuri, Takayuki, Kosaka, Akemi, Nagato, Toshihiro, Kobayashi, Hiroya
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Commentary
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806643/
https://ncbi.nlm.nih.gov/pubmed/29064738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1395995
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