Acute Kynurenine Challenge Disrupts Sleep–Wake Architecture and Impairs Contextual Memory in Adult Rats

STUDY OBJECTIVES: Tryptophan metabolism via the kynurenine pathway may represent a key molecular link between sleep loss and cognitive dysfunction. Modest increases in the kynurenine pathway metabolite kynurenic acid (KYNA), which acts as an antagonist at N-methyl-d-aspartate and α7 nicotinic acetyl...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sleep
Main Authors: Pocivavsek, Ana, Baratta, Annalisa M, Mong, Jessica A, Viechweg, Shaun S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Basic Science of Sleep and Circadian Rhythms
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806560/
https://ncbi.nlm.nih.gov/pubmed/29029302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sleep/zsx141
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker