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Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease

Exposure to the herbicide paraquat (PQ) is associated with an increased risk of idiopathic Parkinson’s disease (PD). Therapies based on PQ’s presumed mechanisms of action have not, however, yielded effective disease therapies. Cellular senescence is an anticancer mechanism that arrests proliferation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Chinta, Shankar J., Woods, Georgia, Demaria, Marco, Rane, Anand, Zou, Ying, McQuade, Amanda, Rajagopalan, Subramanian, Limbad, Chandani, Madden, David T., Campisi, Judith, Andersen, Julie K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806534/
https://ncbi.nlm.nih.gov/pubmed/29386135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.092
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