Digoxin Suppresses Pyruvate Kinase M2 Promoted HIF-1α Transactivation in Steatohepatitis

Sterile inflammation after tissue damage is a ubiquitous response, and yet has the highest amplitude in the liver. This has major clinical consequences with alcoholic and non-alcoholic steatohepatitis (ASH and NASH) accounting for the majority of liver disease in industrialized countries, and both l...

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Foilsithe in:Cell Metab
Main Authors: Ouyang, Xinshou, Han, Sheng-Na, Zhang, Ji-Yuan, Nemeth, Balazs Tamas, Pacher, Pal, Feng, Dechun, Bataller, Ramon, Cabezas, Joaquin, Stärkel, Peter, Caballeria, Joan, Pongratz, Rebecca LePine, Cai, Shi-Ying, Schnabl, Bernd, Hoque, Rafaz, Chen, Yonglin, Yang, Wei-hong, Martinez, Irma Garcia, Wang, Fu-Sheng, Gao, Bin, Torok, Natalie Julia, Kibbey, Richard Glenn, Mehal, Wajahat Zafar
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806149/
https://ncbi.nlm.nih.gov/pubmed/29414684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.01.007
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