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Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells

Deregulated signal transduction and energy metabolism are hallmarks of cancer and both play a fundamental role in tumorigenesis. While it is increasingly recognised that signalling and metabolism are highly interconnected, the underpinning mechanisms of their co-regulation are still largely unknown....

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Detalhes bibliográficos
Publicado no:Metab Eng
Main Authors: Gonçalves, Emanuel, Sciacovelli, Marco, Costa, Ana S.H., Tran, Maxine Gia Binh, Johnson, Timothy Isaac, Machado, Daniel, Frezza, Christian, Saez-Rodriguez, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805855/
https://ncbi.nlm.nih.gov/pubmed/29191787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2017.11.011
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