Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells

BACKGROUND: Loss of function of fumarate hydratase (FH), the mitochondrial tumor suppressor and tricarboxylic acid (TCA) cycle enzyme, is associated with a highly malignant form of papillary and collecting duct renal cell cancer. The accumulation of fumarate in these cells has been linked to the tum...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Zheng, Liang, MacKenzie, Elaine D, Karim, Saadia A, Hedley, Ann, Blyth, Karen, Kalna, Gabriela, Watson, David G, Szlosarek, Peter, Frezza, Christian, Gottlieb, Eyal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108060/
https://ncbi.nlm.nih.gov/pubmed/24280230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-12
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller