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A pilot resting-state functional connectivity study of the kynurenine pathway in adolescents with depression and healthy controls
BACKGROUND: The neuroimmunological kynurenine pathway (KP) has been hypothesized to play a role in depressive/anhedonic symptoms and related CNS disturbances. Indoleamine 2,3-dioxygenase (IDO) is the rate limiting enzyme which leads to neurotrophic [kynurenic acid (KA)] and neurotoxic [Quinolinic ac...
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| Publicado no: | J Affect Disord |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5805652/ https://ncbi.nlm.nih.gov/pubmed/29254065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2017.11.040 |
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