A pilot resting-state functional connectivity study of the kynurenine pathway in adolescents with depression and healthy controls

BACKGROUND: The neuroimmunological kynurenine pathway (KP) has been hypothesized to play a role in depressive/anhedonic symptoms and related CNS disturbances. Indoleamine 2,3-dioxygenase (IDO) is the rate limiting enzyme which leads to neurotrophic [kynurenic acid (KA)] and neurotoxic [Quinolinic ac...

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Bibliografiske detaljer
Udgivet i:J Affect Disord
Main Authors: DeWitt, Samuel J., Bradley, Kailyn A., Lin, Na, Yu, Chunli, Gabbay, Vilma
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805652/
https://ncbi.nlm.nih.gov/pubmed/29254065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2017.11.040
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