The role of the kynurenine pathway in suicidality in adolescent major depressive disorder

The neuroimmunological kynurenine pathway (KP) has been implicated in major depressive disorder (MDD) in adults and adolescents, most recently in suicidality in adults. The KP is initiated by the enzyme indoleamine 2,3-dioxygenase (IDO), which degrades tryptophan (TRP) into kynurenine (KYN) en route...

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Gepubliceerd in:Psychiatry Res
Hoofdauteurs: Bradley, Kailyn A. L., Case, Julia A. C., Khan, Omar, Ricart, Thomas, Hanna, Amira, Alonso, Carmen M., Gabbay, Vilma
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430385/
https://ncbi.nlm.nih.gov/pubmed/25865484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psychres.2015.03.031
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