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Inhibition of O-GlcNAcase sensitizes apoptosis and reverses bortezomib resistance in mantle cell lymphoma through modification of truncated Bid

Aberrant energy metabolism represents a hallmark of cancer and contributes to numerous aggressive behaviors of cancer cells, including cell death and survival. Despite the poor prognosis of mantle cell lymphoma (MCL), due to the inevitable development of drug resistance, metabolic reprograming of MC...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Luanpitpong, Sudjit, Chanthra, Nawin, Janan, Montira, Poohadsuan, Jirarat, Samart, Parinya, U-Pratya, Yaowalak, Rojanasakul, Yon, Issaragrisil, Surapol
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805589/
https://ncbi.nlm.nih.gov/pubmed/29167312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0390
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