Hyper-O-GlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma

Aberrant metabolism in hexosamine biosynthetic pathway (HBP) has been observed in several cancers, affecting cellular signaling and tumor progression. However, the role of O-GlcNAcylation, a post-translational modification through HBP flux, in apoptosis remains unclear. Here, we found that hyper-O-G...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Luanpitpong, Sudjit, Angsutararux, Paweorn, Samart, Parinya, Chanthra, Nawin, Chanvorachote, Pithi, Issaragrisil, Surapol
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587763/
https://ncbi.nlm.nih.gov/pubmed/28878262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10886-x
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items