Ontogeny-related pharmacogene changes in the pediatric liver transcriptome

OBJECTIVES: The majority of drug dosing studies are based on adult populations, with modification of the dosing for children based on size and weight. This rudimentary approach for drug dosing children is limited, as biologically a child can differ from an adult in far more aspects than just size an...

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Bibliografiske detaljer
Udgivet i:Pharmacogenet Genomics
Main Authors: Meier, Richard, Bi, Chengpeng, Gaedigk, Roger, Heruth, Daniel P., Ye, Shui Qing, Leeder, J. Steven, Fridley, Brooke L.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805126/
https://ncbi.nlm.nih.gov/pubmed/29360682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000326
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