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Hederagenin Induces Apoptosis in Cisplatin-Resistant Head and Neck Cancer Cells by Inhibiting the Nrf2-ARE Antioxidant Pathway

Acquired resistance to cisplatin is the most common reason for the failure of cisplatin chemotherapy. Hederagenin, triterpenoids extracted from ivy leaves, exhibits antitumor activity in various types of cancer. However, the therapeutic potential of hederagenin in head and neck cancer (HNC) has rema...

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Detalles Bibliográficos
Publicado en:Oxid Med Cell Longev
Main Authors: Kim, Eun Hye, Baek, Seungho, Shin, Daiha, Lee, Jaewang, Roh, Jong-Lyel
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804377/
https://ncbi.nlm.nih.gov/pubmed/29456786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5498908
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