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Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis

Artesunate, an anti-malarial drug, has been repurposed as an anticancer drug due to its induction of cell death via reactive oxygen species (ROS) production. However, the molecular mechanisms regulating cancer cell death and the resistance of cells to artesunate remain unclear. We investigated the m...

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Detalhes bibliográficos
Main Authors: Jong-Lyel Roh, Eun Hye Kim, Hyejin Jang, Daiha Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017-04-01
Colecção:Redox Biology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231716303731
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