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Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis

Artesunate, an anti-malarial drug, has been repurposed as an anticancer drug due to its induction of cell death via reactive oxygen species (ROS) production. However, the molecular mechanisms regulating cancer cell death and the resistance of cells to artesunate remain unclear. We investigated the m...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Roh, Jong-Lyel, Kim, Eun Hye, Jang, Hyejin, Shin, Daiha
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198738/
https://ncbi.nlm.nih.gov/pubmed/28012440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.010
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