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A muscle‐specific MuRF1‐E2 network requires stabilization of MuRF1‐E2 complexes by telethonin, a newly identified substrate

BACKGROUND: Muscle wasting is observed in the course of many diseases and also during physiological conditions (disuse, ageing). Skeletal muscle mass is largely controlled by the ubiquitin‐proteasome system and thus by the ubiquitinating enzymes (E2s and E3s) that target substrates for subsequent de...

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Bibliografische gegevens
Gepubliceerd in:J Cachexia Sarcopenia Muscle
Hoofdauteurs: Polge, Cécile, Cabantous, Stéphanie, Deval, Christiane, Claustre, Agnès, Hauvette, Antoine, Bouchenot, Catherine, Aniort, Julien, Béchet, Daniel, Combaret, Lydie, Attaix, Didier, Taillandier, Daniel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803617/
https://ncbi.nlm.nih.gov/pubmed/29271608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12249
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