A muscle‐specific MuRF1‐E2 network requires stabilization of MuRF1‐E2 complexes by telethonin, a newly identified substrate

BACKGROUND: Muscle wasting is observed in the course of many diseases and also during physiological conditions (disuse, ageing). Skeletal muscle mass is largely controlled by the ubiquitin‐proteasome system and thus by the ubiquitinating enzymes (E2s and E3s) that target substrates for subsequent de...

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Veröffentlicht in:J Cachexia Sarcopenia Muscle
Hauptverfasser: Polge, Cécile, Cabantous, Stéphanie, Deval, Christiane, Claustre, Agnès, Hauvette, Antoine, Bouchenot, Catherine, Aniort, Julien, Béchet, Daniel, Combaret, Lydie, Attaix, Didier, Taillandier, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803617/
https://ncbi.nlm.nih.gov/pubmed/29271608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12249
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