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Tyro3-mediated phosphorylation of ACTN4 at tyrosines is FAK-dependent and decreases susceptibility to cleavage by m-Calpain
Tyro3, a member of TAM receptor tyrosine kinase family, has been implicated in the regulation of melanoma progression and survival. In this study, we sought the molecular mechanism of Tyro3 effects avoiding endogenous background by overexpression of Tyro3 in fibroblasts that have negligible levels o...
Shranjeno v:
| izdano v: | Int J Biochem Cell Biol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803314/ https://ncbi.nlm.nih.gov/pubmed/29274473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2017.12.014 |
| Oznake: |
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