Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

The error-free and efficient repair of DNA double-stranded breaks (DSBs) is extremely important for cell survival. RNA has been implicated in the resolution of DNA damage but the mechanism remains poorly understood. Here, we show that miRNA biogenesis enzymes, Drosha and Dicer, control the recruitme...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Lu, Wei-Ting, Hawley, Ben R., Skalka, George L., Baldock, Robert A., Smith, Ewan M., Bader, Aldo S., Malewicz, Michal, Watts, Felicity Z., Wilczynska, Ania, Bushell, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803274/
https://ncbi.nlm.nih.gov/pubmed/29416038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02893-x
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