Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Ataxia with oculomotor apraxia 2 (AOA-2) and amyotrophic lateral sclerosis (ALS4) are neurological disorders caused by mutations in the gene encoding for senataxin (SETX), a putative RNA:DNA helicase involved in transcription and in the maintenance of genome integrity. Here, using ChIP followed by h...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Cohen, Sarah, Puget, Nadine, Lin, Yea-Lih, Clouaire, Thomas, Aguirrebengoa, Marion, Rocher, Vincent, Pasero, Philippe, Canitrot, Yvan, Legube, Gaëlle
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803260/
https://ncbi.nlm.nih.gov/pubmed/29416069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02894-w
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars