Gene expression profiling of prostate tissue identifies chromatin regulation as a potential link between obesity and lethal prostate cancer

BACKGROUND: Obese men are at higher risk of advanced prostate cancer and cancer-specific mortality though the biology underlying this association remains unclear. We examined gene expression profiles of prostate tissue to identify biological processes differentially expressed by obesity status and l...

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Détails bibliographiques
Publié dans:Cancer
Auteurs principaux: Ebot, Ericka M., Gerke, Travis, Labbé, David P., Sinnott, Jennifer A., Zadra, Giorgia, Rider, Jennifer R., Tyekucheva, Svitlana, Wilson, Kathryn M., Kelly, Rachel S., Shui, Irene M., Loda, Massimo, Kantoff, Philip W., Finn, Stephen, Vander Heiden, Matthew G., Brown, Myles, Giovannucci, Edward L., Mucci, Lorelei A.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802874/
https://ncbi.nlm.nih.gov/pubmed/28700821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30831
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