Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1

Studies of induced pluripotent stem cells (iPSCs) from schizophrenia patients and control individuals revealed that the disorder is programmed at the preneuronal stage, involves a common dysregulated mRNA transcriptome, and identified Integrative Nuclear FGFR1 Signaling a common dysregulated mechani...

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Publicado en:Transl Psychiatry
Main Authors: Stachowiak, E. K., Benson, C. A., Narla, S. T., Dimitri, A., Chuye, L. E. Bayona, Dhiman, S., Harikrishnan, K., Elahi, S., Freedman, D., Brennand, K. J., Sarder, P., Stachowiak, M. K.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802550/
https://ncbi.nlm.nih.gov/pubmed/30446636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-017-0054-x
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