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Reliability of human 3D cortical organoid generation
The differentiation of pluripotent stem cells in three-dimensional cultures can recapitulate key aspects of brain development, but protocols are prone to variable results. Here we differentiated multiple human pluripotent stem cell lines for over 100 d using our previously developed approach to gene...
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| Pubblicato in: | Nat Methods |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6677388/ https://ncbi.nlm.nih.gov/pubmed/30573846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0255-0 |
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