Reliability of human 3D cortical organoid generation

The differentiation of pluripotent stem cells in three-dimensional cultures can recapitulate key aspects of brain development, but protocols are prone to variable results. Here we differentiated multiple human pluripotent stem cell lines for over 100 d using our previously developed approach to gene...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Methods
Päätekijät: Yoon, Se-Jin, Elahi, Lubayna S., Pașca, Anca M., Marton, Rebecca M., Gordon, Aaron, Revah, Omer, Miura, Yuki, Walczak, Elisabeth M., Holdgate, Gwendolyn M., Fan, H. Christina, Huguenard, John R., Geschwind, Daniel H., Pașca, Sergiu P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677388/
https://ncbi.nlm.nih.gov/pubmed/30573846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0255-0
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