Ubenimex, an APN inhibitor, could serve as an anti-tumor drug in RT112 and 5637 cells by operating in an Akt-associated manner

Bladder cancer, a common urinary tract tumor, has high mortality and recurrence rates associated with metastasis. Aminopeptidase N (APN) expression and metastasis have been indicated to be associated with one another. Ubenimex may function as an APN inhibitor to inhibit the degradation of the extrac...

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Publicado en:Mol Med Rep
Autores principales: Wang, Xiaoqing, Liu, Yang, Liu, Wei, Zhang, Yongfei, Guo, Feng, Zhang, Lijuan, Cui, Mingyu, Liu, Shuai, Wu, Rongde
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2018
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802231/
https://ncbi.nlm.nih.gov/pubmed/29328441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8402
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