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Sleeping Beauty transposon integrates into non-TA dinucleotides

BACKGROUND: Sleeping Beauty transposon (SB) has become an increasingly important genetic tool for generating mutations in vertebrate cells. It is widely thought that SB exclusively integrates into TA dinucleotides. However, this strict TA-preference has not been rigorously tested in large numbers of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mob DNA
Prif Awduron: Guo, Yabin, Zhang, Yin, Hu, Kaishun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801840/
https://ncbi.nlm.nih.gov/pubmed/29445422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-018-0113-8
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