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Sleeping Beauty transposon integrates into non-TA dinucleotides

BACKGROUND: Sleeping Beauty transposon (SB) has become an increasingly important genetic tool for generating mutations in vertebrate cells. It is widely thought that SB exclusively integrates into TA dinucleotides. However, this strict TA-preference has not been rigorously tested in large numbers of...

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Foilsithe in:Mob DNA
Main Authors: Guo, Yabin, Zhang, Yin, Hu, Kaishun
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801840/
https://ncbi.nlm.nih.gov/pubmed/29445422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-018-0113-8
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