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Sleeping Beauty transposon integrates into non-TA dinucleotides

BACKGROUND: Sleeping Beauty transposon (SB) has become an increasingly important genetic tool for generating mutations in vertebrate cells. It is widely thought that SB exclusively integrates into TA dinucleotides. However, this strict TA-preference has not been rigorously tested in large numbers of...

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Bibliografske podrobnosti
izdano v:Mob DNA
Main Authors: Guo, Yabin, Zhang, Yin, Hu, Kaishun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801840/
https://ncbi.nlm.nih.gov/pubmed/29445422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-018-0113-8
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