MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer

Telomerase consists of at least two essential elements, an RNA component hTR or TERC that contains the template for telomere DNA addition and a catalytic reverse transcriptase (TERT). While expression of TERT has been considered the key rate-limiting component for telomerase activity, increasing evi...

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Détails bibliographiques
Publié dans:J Pathol
Auteurs principaux: Valle, Javier A Baena-Del, Zheng, Qizhi, Esopi, David M, Rubenstein, Michael, Hubbard, Gretchen K, Moncaliano, Maria C, Hruszkewycz, Andrew, Vaghasia, Ajay, Yegnasubramanian, Srinivasan, Wheelan, Sarah J, Meeker, Alan K, Heaphy, Christopher M, Graham, Mindy K, De Marzo, Angelo M
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801764/
https://ncbi.nlm.nih.gov/pubmed/28888037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4980
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