Co‐inhibitory profile and cytotoxicity of CD57(+)PD‐1(–) T cells in end‐stage renal disease patients

Blockade of the CD80/86‐CD28 pathway by belatacept after kidney transplantation is associated with an increased risk of rejection compared with standard, calcineurin inhibitor (CNI)‐based therapy. CD28(–) T cells, which express CD57, are not susceptible to belatacept treatment. High numbers of CD4(+...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Kraaijeveld, R., de Graav, G. N., Dieterich, M., Litjens, N. H. R., Hesselink, D. A., Baan, C. C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801492/
https://ncbi.nlm.nih.gov/pubmed/29027667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13070
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