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Identification of Single Nucleotide Non-coding Driver Mutations in Cancer

Recent whole-genome sequencing studies have identified millions of somatic variants present in tumor samples. Most of these variants reside in non-coding regions of the genome potentially affecting transcriptional and post-transcriptional gene regulation. Although a few hallmark examples of driver m...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Gan, Kok A., Carrasco Pro, Sebastian, Sewell, Jared A., Fuxman Bass, Juan I.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801294/
https://ncbi.nlm.nih.gov/pubmed/29456552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00016
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