A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes

BACKGROUND: Cardiac injury is accompanied by dynamic changes in the expression of microRNAs (miRs), small non-coding RNAs that post-transcriptionally regulate target genes. MiR-125b-5p is downregulated in patients with end-stage dilated and ischemic cardiomyopathy, and has been proposed as a biomark...

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Pubblicato in:J Mol Cell Cardiol
Autori principali: Bayoumi, Ahmed S., Park, Kyoung-mi, Wang, Yongchao, Teoh, Jian-peng, Aonuma, Tatsuya, Tang, Yaoliang, Su, Huabo, Weintraub, Neal L., Kim, Il-man
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800989/
https://ncbi.nlm.nih.gov/pubmed/29122578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.11.003
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