Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1

Multiple myeloma (MM) is a lethal haematological malignancy that arises in the context of a tumour microenvironment that promotes resistance to apoptosis and immune escape. In the present study, we demonstrate that co-culture of MM cells with stromal cells results in increased resistance to cytotoxi...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Bar-Natan, Michal, Stroopinsky, Dina, Luptakova, Katarina, Coll, Maxwell D., Apel, Arie, Rajabi, Hasan, Pyzer, Athalia R., Palmer, Kristen, Reagan, Michaela R., Nahas, Myrna R., Leaf, Rebecca Karp, Jain, Salvia, Arnason, Jon, Ghobrial, Irene M., Anderson, Kenneth C., Kufe, Donald, Rosenblatt, Jacalyn, Avigan, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800979/
https://ncbi.nlm.nih.gov/pubmed/28107546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.14493
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