Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1

Multiple myeloma (MM) is a lethal haematological malignancy that arises in the context of a tumour microenvironment that promotes resistance to apoptosis and immune escape. In the present study, we demonstrate that co-culture of MM cells with stromal cells results in increased resistance to cytotoxi...

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Publicat a:Br J Haematol
Autors principals: Bar-Natan, Michal, Stroopinsky, Dina, Luptakova, Katarina, Coll, Maxwell D., Apel, Arie, Rajabi, Hasan, Pyzer, Athalia R., Palmer, Kristen, Reagan, Michaela R., Nahas, Myrna R., Leaf, Rebecca Karp, Jain, Salvia, Arnason, Jon, Ghobrial, Irene M., Anderson, Kenneth C., Kufe, Donald, Rosenblatt, Jacalyn, Avigan, David
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800979/
https://ncbi.nlm.nih.gov/pubmed/28107546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.14493
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