Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

Recent treatments of leukemias with T cells expressing chimeric antigen receptors (CARs) underline their impressive therapeutic potential but also their risk of severe side effects including cytokine release storms and tumor lysis syndrome. In case of cross-reactivities, CAR T cells may also attack...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Bachmann, Dominik, Aliperta, Roberta, Bergmann, Ralf, Feldmann, Anja, Koristka, Stefanie, Arndt, Claudia, Loff, Simon, Welzel, Petra, Albert, Susann, Kegler, Alexandra, Ehninger, Armin, Cartellieri, Marc, Ehninger, Gerhard, Bornhäuser, Martin, von Bonin, Malte, Werner, Carsten, Pietzsch, Jens, Steinbach, Jörg, Bachmann, Michael
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800918/
https://ncbi.nlm.nih.gov/pubmed/29484126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23556
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