A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

Recent treatments of leukemias with chimeric antigen receptor (CAR) expressing T cells underline their impressive therapeutic potential. However, once adoptively transferred into patients, there is little scope left to shut them down after elimination of tumor cells or in case adverse side effects o...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Albert, Susann, Arndt, Claudia, Feldmann, Anja, Bergmann, Ralf, Bachmann, Dominik, Koristka, Stefanie, Ludwig, Florian, Ziller-Walter, Pauline, Kegler, Alexandra, Gärtner, Sebastian, Schmitz, Marc, Ehninger, Armin, Cartellieri, Marc, Ehninger, Gerhard, Pietzsch, Hans-Jürgen, Pietzsch, Jens, Steinbach, Jörg, Bachmann, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414885/
https://ncbi.nlm.nih.gov/pubmed/28507794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1287246
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