A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

Recent treatments of leukemias with chimeric antigen receptor (CAR) expressing T cells underline their impressive therapeutic potential. However, once adoptively transferred into patients, there is little scope left to shut them down after elimination of tumor cells or in case adverse side effects o...

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Vydáno v:Oncoimmunology
Hlavní autoři: Albert, Susann, Arndt, Claudia, Feldmann, Anja, Bergmann, Ralf, Bachmann, Dominik, Koristka, Stefanie, Ludwig, Florian, Ziller-Walter, Pauline, Kegler, Alexandra, Gärtner, Sebastian, Schmitz, Marc, Ehninger, Armin, Cartellieri, Marc, Ehninger, Gerhard, Pietzsch, Hans-Jürgen, Pietzsch, Jens, Steinbach, Jörg, Bachmann, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414885/
https://ncbi.nlm.nih.gov/pubmed/28507794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1287246
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