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A CRISPR toolbox to study virus–host interactions

Viruses depend on their hosts to complete their replication cycles; they exploit cellular receptors for entry and hijack cellular functions to replicate their genome, assemble progeny virions and spread. Recently, genome-scale CRISPR–Cas screens have been used to identify host factors that are requi...

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Podrobná bibliografie
Vydáno v:Nat Rev Microbiol
Hlavní autoři: Puschnik, Andreas S., Majzoub, Karim, Ooi, Yaw Shin, Carette, Jan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800792/
https://ncbi.nlm.nih.gov/pubmed/28420884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro.2017.29
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