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Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

The Flaviviridae are a family of viruses that cause severe human diseases. For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually worldwide(1). No approved antivirals are available to date and clinical trials with a tetravalen...

詳細記述

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書誌詳細
出版年:Nature
主要な著者: Marceau, Caleb D., Puschnik, Andreas S., Majzoub, Karim, Ooi, Yaw Shin, Brewer, Susan M., Fuchs, Gabriele, Swaminathan, Kavya, Mata, Miguel A., Elias, Joshua E., Sarnow, Peter, Carette, Jan E.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964798/
https://ncbi.nlm.nih.gov/pubmed/27383987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18631
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