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A CRISPR-Based Toolbox for Studying T Cell Signal Transduction

CRISPR/Cas9 system is a powerful technology to perform genome editing in a variety of cell types. To facilitate the application of Cas9 in mapping T cell signaling pathways, we generated a toolbox for large-scale genetic screens in human Jurkat T cells. The toolbox has three different Jurkat cell li...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Chi, Shen, Weiss, Arthur, Wang, Haopeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753324/
https://ncbi.nlm.nih.gov/pubmed/27057542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5052369
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