Lipid droplet formation in Mycobacterium tuberculosis infected macrophages requires IFN-γ/HIF-1α signaling and supports host defense

Lipid droplet (LD) formation occurs during infection of macrophages with numerous intracellular pathogens, including Mycobacterium tuberculosis. It is believed that M. tuberculosis and other bacteria specifically provoke LD formation as a pathogenic strategy in order to create a depot of host lipids...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Pathog
Main Authors: Knight, Matthew, Braverman, Jonathan, Asfaha, Kaleb, Gronert, Karsten, Stanley, Sarah
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800697/
https://ncbi.nlm.nih.gov/pubmed/29370315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006874
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items