Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

Two billion people are latently infected with Mycobacterium tuberculosis (Mtb). Mtb-infected macrophages are likely to be sequestered inside the hypoxic environments of the granuloma and differentiate into lipid-loaded macrophages that contain triacylglycerol (TAG)-filled lipid droplets which may pr...

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מידע ביבליוגרפי
Main Authors: Daniel, Jaiyanth, Maamar, Hédia, Deb, Chirajyoti, Sirakova, Tatiana D., Kolattukudy, Pappachan E.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121879/
https://ncbi.nlm.nih.gov/pubmed/21731490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002093
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