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HIF-1α is an essential mediator of IFN-γ dependent immunity to Mycobacterium tuberculosis

The cytokine IFN-γ coordinates macrophage activation and is essential for control of pathogens including Mycobacterium tuberculosis. However, the mechanisms by which IFN-γ controls M. tuberculosis infection are only partially understood. Here, we show that the transcription factor HIF-1α is an essen...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Braverman, Jonathan, Sogi, Kimberly M., Benjamin, Daniel, Nomura, Daniel K., Stanley, Sarah A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976004/
https://ncbi.nlm.nih.gov/pubmed/27430718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600266
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