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CCN3 suppresses TGF-β1-induced extracellular matrix accumulation in human mesangial cells in vitro
Glomerular sclerosis is characterized by mesangial cell proliferation and progressive extracellular matrix (ECM) accumulation. CCN3 belongs to the CCN family of matrix proteins; increasing evidence suggests that CCN3 is an endogenous negative regulator of the ECM and fibrosis. However, the exact rol...
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| Publicado no: | Acta Pharmacol Sin |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800473/ https://ncbi.nlm.nih.gov/pubmed/28858296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.87 |
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