CCN3 suppresses TGF-β1-induced extracellular matrix accumulation in human mesangial cells in vitro

Glomerular sclerosis is characterized by mesangial cell proliferation and progressive extracellular matrix (ECM) accumulation. CCN3 belongs to the CCN family of matrix proteins; increasing evidence suggests that CCN3 is an endogenous negative regulator of the ECM and fibrosis. However, the exact rol...

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Dettagli Bibliografici
Pubblicato in:Acta Pharmacol Sin
Autori principali: Liu, Hai-fei, Liu, Hong, Lv, Lin-li, Ma, Kun-ling, Wen, Yi, Chen, Long, Liu, Bi-cheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800473/
https://ncbi.nlm.nih.gov/pubmed/28858296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.87
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