CCN3 suppresses TGF-β1-induced extracellular matrix accumulation in human mesangial cells in vitro

Glomerular sclerosis is characterized by mesangial cell proliferation and progressive extracellular matrix (ECM) accumulation. CCN3 belongs to the CCN family of matrix proteins; increasing evidence suggests that CCN3 is an endogenous negative regulator of the ECM and fibrosis. However, the exact rol...

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Detaylı Bibliyografya
Yayımlandı:Acta Pharmacol Sin
Asıl Yazarlar: Liu, Hai-fei, Liu, Hong, Lv, Lin-li, Ma, Kun-ling, Wen, Yi, Chen, Long, Liu, Bi-cheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2018
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800473/
https://ncbi.nlm.nih.gov/pubmed/28858296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.87
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